Functions of the Microbiota for the Physiology of Animal Metaorganisms

Esser, Daniela, Lange, Janina, Marinos, Georgios, Sieber, Michael, Best, Lena, Prasse, Daniela, Bathia, Jay, Rühlemann, Malte C., Boersch, Kathrin, Jaspers, Cornelia and Sommer, Felix (2019) Functions of the Microbiota for the Physiology of Animal Metaorganisms Journal of Innate Immunity, 11 (5). pp. 393-404. DOI 10.1159/000495115.

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Animals are usually regarded as independent entities within their respective environments. However, within an organism, eukaryotes and prokaryotes interact dynamically to form the so-called metaorganism or holobiont, where each partner fulfils its versatile and crucial role. This review focuses on the interplay between microorganisms and multicellular eukaryotes in the context of host physiology, in particular aging and mucus-associated crosstalk. In addition to the interactions between bacteria and the host, we highlight the importance of viruses and nonmodel organisms. Moreover, we discuss current culturing and computational methodologies that allow a deeper understanding of underlying mechanisms controlling the physiology of metaorganisms.

Document Type: Article
Keywords: Metaorganism; Host; Microbiota; Microbiome; Physiology
Research affiliation: OceanRep > GEOMAR > FB3 Marine Ecology > FB3-EV Marine Evolutionary Ecology
Kiel University
Refereed: Yes
DOI etc.: 10.1159/000495115
ISSN: 1662-811X
Projects: CRC 1182
Date Deposited: 07 Jan 2019 14:53
Last Modified: 31 Jul 2019 09:34

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